Sceau Royal will miss the Racing Post Arkle Challenge Trophy Novices' Chase at the Cheltenham Festival after meeting with a setback.
The Alan King-trained six-year-old, who is four from five over fences this season, was the general third favourite for the Grade 1 contest on March 13th.
"It is just a little niggle, but it is enough to stop us and we have taken the decision we will not be taking him to Cheltenham. It is a shame, but this is what happens with horses unfortunately and there is no point hiding it," said King.
"Simon (Munir) and Isaac's (Souede) vet will come down this week and and have a look at him and we will discuss what to do then.
"Put it this way, we won't take any chances with him. If we feel he is not right, we will stop for the season and bring him back next season."