The Gigginstown House Stud pair of Road To Riches and Roi Des Francs are among just seven horses confirmed for the 32Red King George VI Chase at Kempton.
Noel Meade's Road To Riches has been placed in a Cheltenham Gold Cup and a Ryanair Chase on previous visits to Britain, but was pulled up in the Galway Plate and was then only second in the PWC Champion Chase at Gowran Park on his most recent outings.
The Gordon Elliott-trained Roi Des Francs was third to Champagne Fever at Thurles on his first appearance since leaving Willie Mullins.
The Colin Tizzard-trained pair of Cue Card and Thistlecrack are set to lock horns in the King George.
Last season's all-conquering staying hurdler Thistlecrack is unbeaten in three starts over fences, completing his hat-trick in fine style at Newbury last month, and is set to bid for King George glory instead of taking the easier option of running in the 32Red Kauto Star Novices' Chase - better known as the Feltham - on the same afternoon.
Cue Card, last year's King George hero, looked better than ever when winning his third Betfair Chase at Haydock last month.
Paul Nicholls has left in dual King George winner Silviniaco Conti, while last year's Feltham winner Tea For Two has been confirmed by Nick Williams.
Josses Hill has been supplemented by Nicky Henderson following his comfortable victory over Tea For Two in the Peterborough Chase at Huntingdon at the start of the month.